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Detection of cellular senescence within human invasive breast carcinomas distinguishes different breast tumor subtypes

Oncogene-induced senescence is thought to act as a barrier to tumorigenesis by arresting cells at risk of malignant transformation. Nevertheless, numerous findings suggest that senescent cells may conversely promote tumor progression through the development of the senescence-associated secretome the...

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Detalles Bibliográficos
Autores principales: Cotarelo, Cristina L., Schad, Arno, Kirkpatrick, Charles James, Sleeman, Jonathan P., Springer, Erik, Schmidt, Marcus, Thaler, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342706/
https://www.ncbi.nlm.nih.gov/pubmed/27713152
http://dx.doi.org/10.18632/oncotarget.12432