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Detection of cellular senescence within human invasive breast carcinomas distinguishes different breast tumor subtypes
Oncogene-induced senescence is thought to act as a barrier to tumorigenesis by arresting cells at risk of malignant transformation. Nevertheless, numerous findings suggest that senescent cells may conversely promote tumor progression through the development of the senescence-associated secretome the...
Autores principales: | Cotarelo, Cristina L., Schad, Arno, Kirkpatrick, Charles James, Sleeman, Jonathan P., Springer, Erik, Schmidt, Marcus, Thaler, Sonja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342706/ https://www.ncbi.nlm.nih.gov/pubmed/27713152 http://dx.doi.org/10.18632/oncotarget.12432 |
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