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Overexpression of sulfatase-1 in murine hepatocarcinoma Hca-F cell line downregulates mesothelin and leads to reduction in lymphatic metastasis, both in vitro and in vivo
Lymphatic vessels function as transport channels for tumor cells to metastasize from the primary site into the lymph nodes. In this experiment we evaluated the effect of Sulfatase-1 (Sulf-1) on metastasis by upregulating it in murine hepatocarcinoma cell line Hca-F with high lymph node metastatic ra...
Autores principales: | Mahmoud, Salma, Ibrahim, Mohammed, Hago, Ahmed, Huang, Yuhong, Wei, Yuanyi, Zhang, Jun, Zhang, Qingqing, Xiao, Yu, Wang, Jingwen, Adam, Munkaila, Guo, Yu, Wang, Li, Zhou, Shuting, Xin, Boyi, Xuan, Wei, Tang, Jianwu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342722/ https://www.ncbi.nlm.nih.gov/pubmed/27626699 http://dx.doi.org/10.18632/oncotarget.11933 |
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