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Waltonitone inhibits proliferation of hepatoma cells and tumorigenesis via FXR-miR-22-CCNA2 signaling pathway

Waltonitone (WA), an ursane-type pentacyclic triterpene extracted from Gentiana waltonii Burkill, was recently appeared to exert anti-tumor effect. However, the biological underpinnings underlying the role of WA in hepatocellular carcinoma (HCC) cells have not been completely elucidated. Our previou...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Gong, Junting, Wang, Guangyun, Chen, Peng, Yang, Li, Wang, Zhengtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342731/
https://www.ncbi.nlm.nih.gov/pubmed/27738335
http://dx.doi.org/10.18632/oncotarget.12614