MDM2 and CDK4 amplifications are rare events in salivary duct carcinomas

Salivary duct carcinoma (SDC) is an aggressive adenocarcinoma of the salivary glands associated with poor clinical outcome. SDCs are known to carry TP53 mutations in about 50%, however, only little is known about alternative pathogenic mechanisms within the p53 regulatory network. Particularly, data...

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Detalles Bibliográficos
Autores principales: Grünewald, Inga, Trautmann, Marcel, Busch, Alina, Bauer, Larissa, Huss, Sebastian, Schweinshaupt, Petra, Vollbrecht, Claudia, Odenthal, Margarete, Quaas, Alexander, Büttner, Reinhard, Meyer, Moritz F., Beutner, Dirk, Hüttenbrink, Karl-Bernd, Wardelmann, Eva, Stenner, Markus, Hartmann, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342738/
https://www.ncbi.nlm.nih.gov/pubmed/27662657
http://dx.doi.org/10.18632/oncotarget.12127

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