Promoter methylation of PCDH10 by HOTAIR regulates the progression of gastrointestinal stromal tumors

HOTAIR, a long non-coding RNA (lncRNA), plays a crucial role in tumor initiation and metastasis by interacting with the PRC2 complex and the modulation of its target genes. The role of HOTAIR in gastrointestinal stromal tumors (GISTs) is remains unclear. Herein we investigate the mechanism of HOTAIR...

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Detalles Bibliográficos
Autores principales: Lee, Na Keum, Lee, Jung Hwa, Kim, Won Kyu, Yun, Seongju, Youn, Young Hoon, Park, Chan Hyuk, Choi, Yun Young, Kim, Hogeun, Lee, Sang Kil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342742/
https://www.ncbi.nlm.nih.gov/pubmed/27659532
http://dx.doi.org/10.18632/oncotarget.12171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342742/
https://www.ncbi.nlm.nih.gov/pubmed/27659532
http://dx.doi.org/10.18632/oncotarget.12171

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