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Tumor-specific gene therapy for pancreatic cancer using human neural stem cells encoding carboxylesterase

Advanced pancreatic cancer is one of the most lethal malignant human diseases lacking effective treatment. Its extremely low survival rate necessitates development of novel therapeutic approach. Human neural stem cells (NSCs) are known to have tumor-tropic effect. We genetically engineered them to e...

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Detalles Bibliográficos
Autores principales: Choi, Sung S., Yoon, Kichul, Choi, Seon-A, Yoon, Seung-Bin, Kim, Seung U., Lee, Hong J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342743/
https://www.ncbi.nlm.nih.gov/pubmed/27659534
http://dx.doi.org/10.18632/oncotarget.12173