Extrachromosomal HPV-16 LCR transcriptional activation by HDACi opposed by cellular differentiation and DNA integration

Histone deacetylase inhibitors (HDACi) have been shown to render HPV-carrying cells susceptible to intrinsic and extrinsic apoptotic signals. As such, these epigenetic drugs have entered clinical trials in the effort to treat cervical cancer. Here, we studied the effect of common HDACi, with an emph...

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Detalles Bibliográficos
Autores principales: Bojilova, Ekaterina Dimitrova, Weyn, Christine, Antoine, Marie-Hélène, Fontaine, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342758/
https://www.ncbi.nlm.nih.gov/pubmed/27705914
http://dx.doi.org/10.18632/oncotarget.12263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342758/
https://www.ncbi.nlm.nih.gov/pubmed/27705914
http://dx.doi.org/10.18632/oncotarget.12263

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