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c-MYC drives histone demethylase PHF8 during neuroendocrine differentiation and in castration-resistant prostate cancer

Epigenetic factors play critical roles in prostate cancer (PCa) development. However, how they contribute to neuroendocrine differentiation (NED) and castration-resistant PCa (CRPC) is not fully understood. Using bioinformatics and biochemical approaches to analyze cell-based models of NED and CRPC,...

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Detalles Bibliográficos
Autores principales: Maina, Peterson Kariuki, Shao, Peng, Liu, Qi, Fazli, Ladan, Tyler, Scott, Nasir, Moman, Dong, Xuesen, Qi, Hank Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342763/
https://www.ncbi.nlm.nih.gov/pubmed/27689328
http://dx.doi.org/10.18632/oncotarget.12310