SIRT1-mediated downregulation of p27(Kip1) is essential for overcoming contact inhibition of Kaposi's sarcoma-associated herpesvirus transformed cells

Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic virus associated with Kaposi's sarcoma (KS), a malignancy commonly found in AIDS patients. Despite intensive studies in the last two decades, the mechanism of KSHV-induced cellular transformation and tumorigenesis remains uncle...

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Detalles Bibliográficos
Autores principales: He, Meilan, Yuan, Hongfeng, Tan, Brandon, Bai, Rosemary, Kim, Heon Seok, Bae, Sangsu, Che, Lu, Kim, Jin-Soo, Gao, Shou-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342771/
https://www.ncbi.nlm.nih.gov/pubmed/27708228
http://dx.doi.org/10.18632/oncotarget.12359

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