Exploring the interactions of the RAS family in the human protein network and their potential implications in RAS-directed therapies

RAS proteins are the founding members of the RAS superfamily of GTPases. They are involved in key signaling pathways regulating essential cellular functions such as cell growth and differentiation. As a result, their deregulation by inactivating mutations often results in aberrant cell proliferation...

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Detalles Bibliográficos
Autores principales: Bueno, Anibal, Morilla, Ian, Diez, Diego, Moya-Garcia, Aurelio A., Lozano, José, Ranea, Juan A.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342780/
https://www.ncbi.nlm.nih.gov/pubmed/27713118
http://dx.doi.org/10.18632/oncotarget.12416

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