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Phosphoproteomics reveals ALK promote cell progress via RAS/JNK pathway in neuroblastoma
Emerging evidence suggests receptor tyrosine kinase ALK as a promising therapeutic target in neuroblastoma. However, clinical trials reveal that a limited proportion of ALK-positive neuroblastoma patients experience clinical benefits from Crizotinib, a clinically approved specific inhibitor of ALK....
Autores principales: | Chen, Kai, Lv, Fan, Xu, Guofeng, Zhang, Min, Wu, Yeming, Wu, Zhixiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342791/ https://www.ncbi.nlm.nih.gov/pubmed/27732954 http://dx.doi.org/10.18632/oncotarget.12513 |
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