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Combination effect of therapies targeting the PI3K- and AR-signaling pathways in prostate cancer

Several promising targeted-therapeutics for prostate cancer (PCa), primarily affecting the androgen receptor (AR) and the PI3K/AKT/mTOR-pathway, are in various phases of development. However, despite promise, single-agent inhibitors targeting the two pathways have not shown long-term benefits, perha...

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Detalles Bibliográficos
Autores principales:	Yadav, Shalini Singh, Li, Jinyi, Stockert, Jennifer A., O'Connor, James, Herzog, Bryan, Elaiho, Cordelia, Galsky, Matthew D., Tewari, Ashutosh Kumar, Yadav, Kamlesh Kumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342806/ https://www.ncbi.nlm.nih.gov/pubmed/27783994 http://dx.doi.org/10.18632/oncotarget.12771

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