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Dynamic lipopolysaccharide transfer cascade to TLR4/MD2 complex via LBP and CD14

Toll-like receptor 4 (TLR4) together with MD2, one of the key pattern recognition receptors for a pathogen-associated molecular pattern, activates innate immunity by recognizing lipopolysaccharide (LPS) of Gram-negative bacteria. Although LBP and CD14 catalyze LPS transfer to the TLR4/MD2 complex, t...

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Detalles Bibliográficos
Autores principales:	Kim, Soo Jin, Kim, Ho Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2017
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342866/ https://www.ncbi.nlm.nih.gov/pubmed/28115037 http://dx.doi.org/10.5483/BMBRep.2017.50.2.011

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