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The role of extracellular biophysical cues in modulating the Hippo-YAP pathway

The Hippo signaling pathway plays an essential role in adult-tissue homeostasis and organ-size control. In Drosophila and vertebrates, it consists of a highly conserved kinase cascade, which involves MST and Lats that negatively regulate the activity of the downstream transcription coactivators, YAP...

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Detalles Bibliográficos
Autor principal: Mo, Jung-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342869/
https://www.ncbi.nlm.nih.gov/pubmed/27916025
http://dx.doi.org/10.5483/BMBRep.2017.50.2.199