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The role of extracellular biophysical cues in modulating the Hippo-YAP pathway
The Hippo signaling pathway plays an essential role in adult-tissue homeostasis and organ-size control. In Drosophila and vertebrates, it consists of a highly conserved kinase cascade, which involves MST and Lats that negatively regulate the activity of the downstream transcription coactivators, YAP...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Korean Society for Biochemistry and Molecular Biology
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342869/ https://www.ncbi.nlm.nih.gov/pubmed/27916025 http://dx.doi.org/10.5483/BMBRep.2017.50.2.199 |