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Subclonal diversity arises early even in small colorectal tumours and contributes to differential growth fates

OBJECTIVE AND DESIGN: The goal of the study was to determine whether the mutational profile of early colorectal polyps correlated with growth behaviour. The growth of small polyps (6–9 mm) that were first identified during routine screening of patients was monitored over time by interval imaging wit...

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Detalles Bibliográficos
Autores principales: Sievers, Chelsie K, Zou, Luli S, Pickhardt, Perry J, Matkowskyj, Kristina A, Albrecht, Dawn M, Clipson, Linda, Bacher, Jeffery W, Pooler, B Dustin, Moawad, Fouad J, Cash, Brooks D, Reichelderfer, Mark, Vo, Tien N, Newton, Michael A, Larget, Bret R, Halberg, Richard B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342955/
https://www.ncbi.nlm.nih.gov/pubmed/27609830
http://dx.doi.org/10.1136/gutjnl-2016-312232