Nortriptyline, a tricyclic antidepressant, inhibits voltage-dependent K(+) channels in coronary arterial smooth muscle cells

We demonstrated the effect of nortriptyline, a tricyclic antidepressant drug and serotonin reuptake inhibitor, on voltage-dependent K(+) (Kv) channels in freshly isolated rabbit coronary arterial smooth muscle cells using a whole-cell patch clamp technique. Nortriptyline inhibited Kv currents in a c...

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Detalles Bibliográficos
Autores principales: Shin, Sung Eun, Li, Hongliang, Kim, Han Sol, Kim, Hye Won, Seo, Mi Seon, Ha, Kwon-Soo, Han, Eun-Taek, Hong, Seok-Ho, Firth, Amy L., Choi, Il-Whan, Bae, Young Min, Park, Won Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343056/
https://www.ncbi.nlm.nih.gov/pubmed/28280416
http://dx.doi.org/10.4196/kjpp.2017.21.2.225

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