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Synthesis, characterization and pharmacological evaluation of pyrazolyl urea derivatives as potential anti-inflammatory agents

p38α mitogen activated protein kinase (MAPK) inhibitors provide a novel approach for the treatment of inflammatory disorders. A series of fifteen pyrazolyl urea derivatives (3a—o) were synthesized and evaluated for their p38α MAPK inhibition and antioxidant potential. Compounds 3a—e, 3g and 3h showe...

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Detalles Bibliográficos
Autores principales:	Somakala, Kanagasabai, Amir, Mohammad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343109/ https://www.ncbi.nlm.nih.gov/pubmed/28303231 http://dx.doi.org/10.1016/j.apsb.2016.08.006

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