A novel class of apical sodium--dependent bile salt transporter inhibitors: 1-(2,4-bifluorophenyl)-7-dialkylamino-1,8-naphthyridine-3-carboxamides

The apical sodium--dependent bile acid transporter (ASBT) is the main transporter to promote re-absorption of bile acids from the intestinal tract into the enterohepatic circulation. Inhibition of ASBT could increase the excretion of bile acids, thus increasing bile acid synthesis and consequently c...

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Detalles Bibliográficos
Autores principales: Liu, Hongtao, Pang, Guoxun, Ren, Jinfeng, Zhao, Yue, Wang, Juxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343113/
https://www.ncbi.nlm.nih.gov/pubmed/28303230
http://dx.doi.org/10.1016/j.apsb.2016.11.005

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