Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection

INTRODUCTION: Globally, extra-intestinal pathogenic Escherichia coli are one of the predominant causative agents of bacteraemia. CASE PRESENTATION: This case report outlines a presentation of community-acquired pyelonephritis and secondary bloodstream infection in an 81-year-old man. Laboratory inve...

Descripción completa

Detalles Bibliográficos
Autores principales: Mac Aogáin, Micheál, Miajlovic, Helen, Moloney, Geraldine, Chotirmall, Sanjay H., Rogers, Thomas R., Smith, Stephen G. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343142/
https://www.ncbi.nlm.nih.gov/pubmed/28348784
http://dx.doi.org/10.1099/jmmcr.0.005061
Descripción
Sumario:INTRODUCTION: Globally, extra-intestinal pathogenic Escherichia coli are one of the predominant causative agents of bacteraemia. CASE PRESENTATION: This case report outlines a presentation of community-acquired pyelonephritis and secondary bloodstream infection in an 81-year-old man. Laboratory investigations revealed that the causative isolate was a multi-drug-resistant E. coli of a novel multi-locus sequence type. This sequence type (ST) was designated ST-458 and was most closely related to the globally prevalent ST-131 lineage. CONCLUSION: This is the first report of a novel E. coli ST, ST-458, which caused pyelonephritis and bacteraemia.

Ejemplares similares