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Sternal wound infection caused by Gordonia bronchialis: identification by MALDI-TOF MS

INTRODUCTION: Gordonia spp. infections are uncommon. However, a few clinical cases have been reported in the literature, particularly those involving immunocompromised hosts. Advanced microbiology diagnosis techniques, such as matrix-assisted laser desorption ionization-time of flight MS (MALDI-TOF...

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Autores principales: Rodriguez-Lozano, Jesús, Pérez-Llantada, Enrique, Agüero, Jesús, Rodríguez-Fernández, Ana, Ruiz de Alegria, Carlos, Martinez-Martinez, Luis, Calvo, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343147/
https://www.ncbi.nlm.nih.gov/pubmed/28348789
http://dx.doi.org/10.1099/jmmcr.0.005067
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author Rodriguez-Lozano, Jesús
Pérez-Llantada, Enrique
Agüero, Jesús
Rodríguez-Fernández, Ana
Ruiz de Alegria, Carlos
Martinez-Martinez, Luis
Calvo, Jorge
author_facet Rodriguez-Lozano, Jesús
Pérez-Llantada, Enrique
Agüero, Jesús
Rodríguez-Fernández, Ana
Ruiz de Alegria, Carlos
Martinez-Martinez, Luis
Calvo, Jorge
author_sort Rodriguez-Lozano, Jesús
collection PubMed
description INTRODUCTION: Gordonia spp. infections are uncommon. However, a few clinical cases have been reported in the literature, particularly those involving immunocompromised hosts. Advanced microbiology diagnosis techniques, such as matrix-assisted laser desorption ionization-time of flight MS (MALDI-TOF MS), have been recently introduced in clinical microbiology laboratories in order to improve microbial identification, resulting in better patient management. CASE PRESENTATION: Here, we present a new clinical case of persistent wound infection caused by Gordonia bronchialis in a 64-year-old woman after a mitral valve replacement, using two MALDI-TOF-based systems for identifying this micro-organism. CONCLUSION: Both MALDI-TOF systems were able to identify Gordonia spp.; thus, providing a useful tool that overcomes the current limitations of phenotypic identification associated with this micro-organism. Although the technique validation deserves additional verification, our study provides guidance about MALDI-TOF as a fast and easy method for Gordonia spp. identification.
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spelling pubmed-53431472017-03-27 Sternal wound infection caused by Gordonia bronchialis: identification by MALDI-TOF MS Rodriguez-Lozano, Jesús Pérez-Llantada, Enrique Agüero, Jesús Rodríguez-Fernández, Ana Ruiz de Alegria, Carlos Martinez-Martinez, Luis Calvo, Jorge JMM Case Rep Case Report INTRODUCTION: Gordonia spp. infections are uncommon. However, a few clinical cases have been reported in the literature, particularly those involving immunocompromised hosts. Advanced microbiology diagnosis techniques, such as matrix-assisted laser desorption ionization-time of flight MS (MALDI-TOF MS), have been recently introduced in clinical microbiology laboratories in order to improve microbial identification, resulting in better patient management. CASE PRESENTATION: Here, we present a new clinical case of persistent wound infection caused by Gordonia bronchialis in a 64-year-old woman after a mitral valve replacement, using two MALDI-TOF-based systems for identifying this micro-organism. CONCLUSION: Both MALDI-TOF systems were able to identify Gordonia spp.; thus, providing a useful tool that overcomes the current limitations of phenotypic identification associated with this micro-organism. Although the technique validation deserves additional verification, our study provides guidance about MALDI-TOF as a fast and easy method for Gordonia spp. identification. Microbiology Society 2016-10-31 /pmc/articles/PMC5343147/ /pubmed/28348789 http://dx.doi.org/10.1099/jmmcr.0.005067 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Rodriguez-Lozano, Jesús
Pérez-Llantada, Enrique
Agüero, Jesús
Rodríguez-Fernández, Ana
Ruiz de Alegria, Carlos
Martinez-Martinez, Luis
Calvo, Jorge
Sternal wound infection caused by Gordonia bronchialis: identification by MALDI-TOF MS
title Sternal wound infection caused by Gordonia bronchialis: identification by MALDI-TOF MS
title_full Sternal wound infection caused by Gordonia bronchialis: identification by MALDI-TOF MS
title_fullStr Sternal wound infection caused by Gordonia bronchialis: identification by MALDI-TOF MS
title_full_unstemmed Sternal wound infection caused by Gordonia bronchialis: identification by MALDI-TOF MS
title_short Sternal wound infection caused by Gordonia bronchialis: identification by MALDI-TOF MS
title_sort sternal wound infection caused by gordonia bronchialis: identification by maldi-tof ms
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343147/
https://www.ncbi.nlm.nih.gov/pubmed/28348789
http://dx.doi.org/10.1099/jmmcr.0.005067
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