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Early-Onset Signet-Ring Cell Adenocarcinoma of the Colon: A Case Report and Review of the Literature
Colorectal cancer (CRC) remains the second leading cause of cancer-related deaths in the United States. While a decline has been observed in the older population, the occurrence of CRC in the adolescent and young adult (AYA) population has increased over the past two decades. The histopathologic cha...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343248/ https://www.ncbi.nlm.nih.gov/pubmed/28326211 http://dx.doi.org/10.1155/2017/2832180 |
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author | Khan, Maliha Korphaisarn, Krittiya Saif, Aneeqa Foo, Wai C. Kopetz, Scott |
author_facet | Khan, Maliha Korphaisarn, Krittiya Saif, Aneeqa Foo, Wai C. Kopetz, Scott |
author_sort | Khan, Maliha |
collection | PubMed |
description | Colorectal cancer (CRC) remains the second leading cause of cancer-related deaths in the United States. While a decline has been observed in the older population, the occurrence of CRC in the adolescent and young adult (AYA) population has increased over the past two decades. The histopathologic characteristics and clinical behavior of CRC in AYA patients have been shown to be distinct from those of CRC in older adults. The rarer subtypes of CRC such as mucinous adenocarcinoma and signet-ring cell carcinoma are associated with a poorer prognosis compared to the more common subtypes. Here we report a case of a 20-year-old man who was diagnosed with stage IVB (T4 N2 M1, with peritoneal carcinomatosis) signet-ring cell adenocarcinoma of the colon. The scarcity of information on these rarer subtypes merits further study and investigation. |
format | Online Article Text |
id | pubmed-5343248 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-53432482017-03-21 Early-Onset Signet-Ring Cell Adenocarcinoma of the Colon: A Case Report and Review of the Literature Khan, Maliha Korphaisarn, Krittiya Saif, Aneeqa Foo, Wai C. Kopetz, Scott Case Rep Oncol Med Case Report Colorectal cancer (CRC) remains the second leading cause of cancer-related deaths in the United States. While a decline has been observed in the older population, the occurrence of CRC in the adolescent and young adult (AYA) population has increased over the past two decades. The histopathologic characteristics and clinical behavior of CRC in AYA patients have been shown to be distinct from those of CRC in older adults. The rarer subtypes of CRC such as mucinous adenocarcinoma and signet-ring cell carcinoma are associated with a poorer prognosis compared to the more common subtypes. Here we report a case of a 20-year-old man who was diagnosed with stage IVB (T4 N2 M1, with peritoneal carcinomatosis) signet-ring cell adenocarcinoma of the colon. The scarcity of information on these rarer subtypes merits further study and investigation. Hindawi Publishing Corporation 2017 2017-02-23 /pmc/articles/PMC5343248/ /pubmed/28326211 http://dx.doi.org/10.1155/2017/2832180 Text en Copyright © 2017 Maliha Khan et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Khan, Maliha Korphaisarn, Krittiya Saif, Aneeqa Foo, Wai C. Kopetz, Scott Early-Onset Signet-Ring Cell Adenocarcinoma of the Colon: A Case Report and Review of the Literature |
title | Early-Onset Signet-Ring Cell Adenocarcinoma of the Colon: A Case Report and Review of the Literature |
title_full | Early-Onset Signet-Ring Cell Adenocarcinoma of the Colon: A Case Report and Review of the Literature |
title_fullStr | Early-Onset Signet-Ring Cell Adenocarcinoma of the Colon: A Case Report and Review of the Literature |
title_full_unstemmed | Early-Onset Signet-Ring Cell Adenocarcinoma of the Colon: A Case Report and Review of the Literature |
title_short | Early-Onset Signet-Ring Cell Adenocarcinoma of the Colon: A Case Report and Review of the Literature |
title_sort | early-onset signet-ring cell adenocarcinoma of the colon: a case report and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343248/ https://www.ncbi.nlm.nih.gov/pubmed/28326211 http://dx.doi.org/10.1155/2017/2832180 |
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