Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature

Granuloma annulare (GA) is a benign granulomatous skin disorder of unknown etiology. GA is rarely associated with liver diseases. We report a unique case of chronic hepatitis with liver granulomas in a patient with GA. Despite an extensive workup, no clear etiology for the hepatitis was found. Based...

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Autores principales: Alsahafi, Majid, AlJasser, Mohammed I., Kalia, Sunil, Yang, H. M., Ramji, Alnoor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343250/
https://www.ncbi.nlm.nih.gov/pubmed/28326206
http://dx.doi.org/10.1155/2017/8768529
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author Alsahafi, Majid
AlJasser, Mohammed I.
Kalia, Sunil
Yang, H. M.
Ramji, Alnoor
author_facet Alsahafi, Majid
AlJasser, Mohammed I.
Kalia, Sunil
Yang, H. M.
Ramji, Alnoor
author_sort Alsahafi, Majid
collection PubMed
description Granuloma annulare (GA) is a benign granulomatous skin disorder of unknown etiology. GA is rarely associated with liver diseases. We report a unique case of chronic hepatitis with liver granulomas in a patient with GA. Despite an extensive workup, no clear etiology for the hepatitis was found. Based on the possible immune pathophysiology of GA and the presence of liver granulomas, the patient was treated with prednisone and azathioprine which resulted in complete normalization of the liver enzymes and concurrent improvement of GA. The association between liver diseases and GA is reviewed.
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spelling pubmed-53432502017-03-21 Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature Alsahafi, Majid AlJasser, Mohammed I. Kalia, Sunil Yang, H. M. Ramji, Alnoor Case Rep Gastrointest Med Case Report Granuloma annulare (GA) is a benign granulomatous skin disorder of unknown etiology. GA is rarely associated with liver diseases. We report a unique case of chronic hepatitis with liver granulomas in a patient with GA. Despite an extensive workup, no clear etiology for the hepatitis was found. Based on the possible immune pathophysiology of GA and the presence of liver granulomas, the patient was treated with prednisone and azathioprine which resulted in complete normalization of the liver enzymes and concurrent improvement of GA. The association between liver diseases and GA is reviewed. Hindawi Publishing Corporation 2017 2017-02-23 /pmc/articles/PMC5343250/ /pubmed/28326206 http://dx.doi.org/10.1155/2017/8768529 Text en Copyright © 2017 Majid Alsahafi et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Alsahafi, Majid
AlJasser, Mohammed I.
Kalia, Sunil
Yang, H. M.
Ramji, Alnoor
Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature
title Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature
title_full Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature
title_fullStr Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature
title_full_unstemmed Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature
title_short Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature
title_sort chronic hepatitis with liver granulomas in a patient with granuloma annulare: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343250/
https://www.ncbi.nlm.nih.gov/pubmed/28326206
http://dx.doi.org/10.1155/2017/8768529
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