Heat Shock Protein HSP27 Secretion by Ovarian Cancer Cells Is Linked to Intracellular Expression Levels, Occurs Independently of the Endoplasmic Reticulum Pathway and HSP27's Phosphorylation Status, and Is Mediated by Exosome Liberation

The heat shock protein HSP27 has been correlated in ovarian cancer (OC) patients with aggressiveness and chemoresistance and, therefore, represents a promising potential biomarker for OC diagnosis, prognosis, and treatment response. Notably, secretion of soluble HSP27 has been described by a few cel...

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Detalles Bibliográficos
Autores principales: Stope, Matthias B., Klinkmann, Gerd, Diesing, Karoline, Koensgen, Dominique, Burchardt, Martin, Mustea, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343262/
https://www.ncbi.nlm.nih.gov/pubmed/28325957
http://dx.doi.org/10.1155/2017/1575374

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