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Properties of STAT1 and IRF1 enhancers and the influence of SNPs

BACKGROUND: STAT1 and IRF1 collaborate to induce interferon-γ (IFNγ) stimulated genes (ISGs), but the extent to which they act alone or together is unclear. The effect of single nucleotide polymorphisms (SNPs) on in vivo binding is also largely unknown. RESULTS: We show that IRF1 binds at proximal o...

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Detalles Bibliográficos
Autores principales:	Abou El Hassan, Mohamed, Huang, Katherine, Eswara, Manoja B. K., Xu, Zhaodong, Yu, Tao, Aubry, Arthur, Ni, Zuyao, Livne-bar, Izzy, Sangwan, Monika, Ahmad, Mohamad, Bremner, Rod
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343312/ https://www.ncbi.nlm.nih.gov/pubmed/28274199 http://dx.doi.org/10.1186/s12867-017-0084-1

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