Elevated serum autoantibodies against co-inhibitory PD-1 facilitate T cell proliferation and correlate with disease activity in new-onset systemic lupus erythematosus patients

BACKGROUND: Programmed cell death protein 1 (PD-1) plays an important role in immune response regulation as a co-inhibitory signal during T cell activation. However, there is little known about the serum autoantibody profile of PD-1 in systemic lupus erythematosus (SLE), a disease characterized by t...

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Detalles Bibliográficos
Autores principales: Shi, Hui, Ye, Junna, Teng, Jialin, Yin, Yufeng, Hu, Qiongyi, Wu, Xinyao, Liu, Honglei, Cheng, Xiaobing, Su, Yutong, Liu, Mengru, Gu, Juanfang, Lu, Ting, Chen, HaoJie, Zheng, Hui, Sun, Yue, Yang, Chengde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343377/
https://www.ncbi.nlm.nih.gov/pubmed/28274252
http://dx.doi.org/10.1186/s13075-017-1258-4

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