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The Effect of Metformin and GANT61 Combinations on the Radiosensitivity of Prostate Cancer Cells

The anti-diabetes drug metformin has been shown to have anti-neoplastic effects in several tumor models through its effects on energy metabolism and protein synthesis. Recent studies show that metformin also targets Hedgehog (Hh) signaling, a developmental pathway re-activated in several tumor types...

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Detalles Bibliográficos
Autores principales: Gonnissen, Annelies, Isebaert, Sofie, McKee, Chad M., Muschel, Ruth J., Haustermans, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343511/
https://www.ncbi.nlm.nih.gov/pubmed/28208838
http://dx.doi.org/10.3390/ijms18020399

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