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The Effect of Metformin and GANT61 Combinations on the Radiosensitivity of Prostate Cancer Cells
The anti-diabetes drug metformin has been shown to have anti-neoplastic effects in several tumor models through its effects on energy metabolism and protein synthesis. Recent studies show that metformin also targets Hedgehog (Hh) signaling, a developmental pathway re-activated in several tumor types...
Autores principales: | Gonnissen, Annelies, Isebaert, Sofie, McKee, Chad M., Muschel, Ruth J., Haustermans, Karin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343511/ https://www.ncbi.nlm.nih.gov/pubmed/28208838 http://dx.doi.org/10.3390/ijms18020399 |
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