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T cell costimulation blockade blunts pressure overload-induced heart failure

Heart failure (HF) is a leading cause of mortality. Inflammation is implicated in HF, yet clinical trials targeting pro-inflammatory cytokines in HF were unsuccessful, possibly due to redundant functions of individual cytokines. Searching for better cardiac inflammation targets, here we link T cells...

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Detalles Bibliográficos
Autores principales: Kallikourdis, Marinos, Martini, Elisa, Carullo, Pierluigi, Sardi, Claudia, Roselli, Giuliana, Greco, Carolina M., Vignali, Debora, Riva, Federica, Ormbostad Berre, Anne Marie, Stølen, Tomas O., Fumero, Andrea, Faggian, Giuseppe, Di Pasquale, Elisa, Elia, Leonardo, Rumio, Cristiano, Catalucci, Daniele, Papait, Roberto, Condorelli, Gianluigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343521/
https://www.ncbi.nlm.nih.gov/pubmed/28262700
http://dx.doi.org/10.1038/ncomms14680