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PDK2 promotes chondrogenic differentiation of mesenchymal stem cells by upregulation of Sox6 and activation of JNK/MAPK/ERK pathway

This study was undertaken to clarify the role and mechanism of pyruvate dehydrogenase kinase isoform 2 (PDK2) in chondrogenic differentiation of mesenchymal stem cells (MSCs). MSCs were isolated from femurs and tibias of Sprague-Dawley rats, weighing 300-400 g (5 females and 5 males). Overexpression...

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Detalles Bibliográficos
Autores principales:	Wang, H., Shan, X.B., Qiao, Y.J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Associação Brasileira de Divulgação Científica 2017
Materias:	Biomedical Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343558/ https://www.ncbi.nlm.nih.gov/pubmed/28225870 http://dx.doi.org/10.1590/1414-431X20165988

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