Ultrasensitive colorimetric detection of circulating tumor DNA using hybridization chain reaction and the pivot of triplex DNA

This work presents an amplified colorimetric biosensor for circulating tumor DNA (ctDNA), which associates the hybridization chain reaction (HCR) amplification with G-Quadruplex DNAzymes activity through triplex DNA formation. In the presence of ctDNA, HCR occurs. The resulting HCR products are spec...

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Detalles Bibliográficos
Autores principales: Li, Ruimin, Zou, Li, Luo, Yanwei, Zhang, Manjun, Ling, Liansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343571/
https://www.ncbi.nlm.nih.gov/pubmed/28276503
http://dx.doi.org/10.1038/srep44212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343571/
https://www.ncbi.nlm.nih.gov/pubmed/28276503
http://dx.doi.org/10.1038/srep44212

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