Antimicrobial peptide cWFW kills by combining lipid phase separation with autolysis

The synthetic cyclic hexapeptide cWFW (cyclo(RRRWFW)) has a rapid bactericidal activity against both Gram-positive and Gram-negative bacteria. Its detailed mode of action has, however, remained elusive. In contrast to most antimicrobial peptides, cWFW neither permeabilizes the membrane nor transloca...

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Detalles Bibliográficos
Autores principales: Scheinpflug, Kathi, Wenzel, Michaela, Krylova, Oxana, Bandow, Julia E., Dathe, Margitta, Strahl, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343580/
https://www.ncbi.nlm.nih.gov/pubmed/28276520
http://dx.doi.org/10.1038/srep44332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343580/
https://www.ncbi.nlm.nih.gov/pubmed/28276520
http://dx.doi.org/10.1038/srep44332

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