Lugol's iodine identifies dysplastic tissue in precancerous lesions: A clinical trial

INTRODUCTION: Intraepithelial dysplasia, or “invisible” precancerous lesions, provides a challenge for visualization to the surgical team. The prognostic relevance of dysplasia and carcinoma in situ at surgical margins is well documented. MATERIALS AND METHODS: We evaluated the use of Lugol's i...

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Detalles Bibliográficos
Autores principales: Fatima, Shereen, Basu, Rajarshi, Hallur, Neelakamal H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Original Article - Evaluative Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343623/
https://www.ncbi.nlm.nih.gov/pubmed/28299253
http://dx.doi.org/10.4103/2231-0746.200333
Descripción
Sumario:INTRODUCTION: Intraepithelial dysplasia, or “invisible” precancerous lesions, provides a challenge for visualization to the surgical team. The prognostic relevance of dysplasia and carcinoma in situ at surgical margins is well documented. MATERIALS AND METHODS: We evaluated the use of Lugol's iodine in visualizing the surgical margins of dysplastic tissue by an observational study of 100 patients having oral precancerous lesions between June 2013 and March 2016. CONCLUSION: Lugol's iodine is a simple, inexpensive, and apparently effective means of diagnosing and visualizing the surgical margins of the dysplastic tissue in oral precancerous lesions.

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