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Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111

Laminins are cell-adhesive glycoproteins that are essential for basement membrane assembly and function. Integrins are important laminin receptors, but their binding site on the heterotrimeric laminins is poorly defined structurally. We report the crystal structure at 2.13 Å resolution of a minimal...

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Detalles Bibliográficos
Autores principales: Pulido, David, Hussain, Sadaf-Ahmahni, Hohenester, Erhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343747/
https://www.ncbi.nlm.nih.gov/pubmed/28132784
http://dx.doi.org/10.1016/j.str.2017.01.002