Cargando…
Phenotypic and Functional Alterations of Hematopoietic Stem and Progenitor Cells in an In Vitro Leukemia-Induced Microenvironment
An understanding of the cell interactions occurring in the leukemic microenvironment and their functional consequences for the different cell players has therapeutic relevance. By co-culturing mesenchymal stem cells (MSC) with the REH acute lymphocytic leukemia (ALL) cell line, we have established a...
Autores principales: | Vernot, Jean-Paul, Bonilla, Ximena, Rodriguez-Pardo, Viviana, Vanegas, Natalia-Del Pilar |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343770/ https://www.ncbi.nlm.nih.gov/pubmed/28216566 http://dx.doi.org/10.3390/ijms18020199 |
Ejemplares similares
-
Acute Leukemia Induces Senescence and Impaired Osteogenic Differentiation in Mesenchymal Stem Cells Endowing Leukemic Cells with Functional Advantages
por: Bonilla, Ximena, et al.
Publicado: (2019) -
Loss of quiescence and self-renewal capacity of hematopoietic stem cell in an in vitro leukemic niche
por: Vanegas, Natalia-Del Pilar, et al.
Publicado: (2017) -
Mesenchymal stem cells promote a primitive phenotype CD34+c-kit+ in human cord blood-derived hematopoietic stem cells during ex vivo expansion
por: Rodríguez-Pardo, Viviana M., et al.
Publicado: (2012) -
Leukemia-Induced Cellular Senescence and Stemness Alterations in Mesenchymal Stem Cells Are Reversible upon Withdrawal of B-Cell Acute Lymphoblastic Leukemia Cells
por: Vanegas, Natalia-Del Pilar, et al.
Publicado: (2021) -
Generation of Organotypic Multicellular Spheres by Magnetic Levitation: Model for the Study of Human Hematopoietic Stem Cells Microenvironment
por: Mejía-Cruz, Claudia Camila, et al.
Publicado: (2019)