GGCX-Associated Phenotypes: An Overview in Search of Genotype-Phenotype Correlations

Gamma-carboxylation, performed by gamma-glutamyl carboxylase (GGCX), is an enzymatic process essential for activating vitamin K-dependent proteins (VKDP) with important functions in various biological processes. Mutations in the encoding GGCX gene are associated with multiple phenotypes, amongst whi...

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Detalles Bibliográficos
Autores principales: De Vilder, Eva Y. G., Debacker, Jens, Vanakker, Olivier M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343777/
https://www.ncbi.nlm.nih.gov/pubmed/28125048
http://dx.doi.org/10.3390/ijms18020240

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