HDAC Inhibitors and RECK Modulate Endoplasmic Reticulum Stress in Tumor Cells

In the tumor microenvironment hypoxia and nutrient deprived states can induce endoplasmic reticulum (ER) stress. If ER stress is not relieved, the tumor cells may become apoptotic. Therefore, targeting ER homeostasis is a potential strategy for cancer treatment. Various chemotherapeutic agents inclu...

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Detalles Bibliográficos
Autores principales: Chen, Yun, Tsai, Ya-Hui, Tseng, Sheng-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343794/
https://www.ncbi.nlm.nih.gov/pubmed/28134767
http://dx.doi.org/10.3390/ijms18020258

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