Deguelin Potentiates Apoptotic Activity of an EGFR Tyrosine Kinase Inhibitor (AG1478) in PIK3CA-Mutated Head and Neck Squamous Cell Carcinoma

Head and neck squamous cell carcinoma (HNSCC) is known to be intrinsically resistant to inhibitors for epidermal growth factor receptor (EGFR). Until now, clinical outcomes for HNSCC using EGFR inhibitors as single agents have yielded disappointing results. Here, we aimed to study whether combinator...

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Detalles Bibliográficos
Autores principales: Baba, Yuh, Maeda, Toyonobu, Suzuki, Atsuko, Takada, Satoshi, Fujii, Masato, Kato, Yasumasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343798/
https://www.ncbi.nlm.nih.gov/pubmed/28134774
http://dx.doi.org/10.3390/ijms18020262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343798/
https://www.ncbi.nlm.nih.gov/pubmed/28134774
http://dx.doi.org/10.3390/ijms18020262

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