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Dimethyl Fumarate Therapy Significantly Improves the Responsiveness of T Cells in Multiple Sclerosis Patients for Immunoregulation by Regulatory T Cells

Multiple sclerosis (MS) is a chronic autoimmune disease caused by an insufficient suppression of autoreactive T lymphocytes. One reason for the lack of immunological control is the reduced responsiveness of T effector cells (Teff) for the suppressive properties of regulatory T cells (Treg), a proces...

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Detalles Bibliográficos
Autores principales: Schlöder, Janine, Berges, Carsten, Luessi, Felix, Jonuleit, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343807/
https://www.ncbi.nlm.nih.gov/pubmed/28134847
http://dx.doi.org/10.3390/ijms18020271