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Reduced SHARPIN and LUBAC Formation May Contribute to CCl(4)- or Acetaminophen-Induced Liver Cirrhosis in Mice

Linear ubiquitin chain assembly complex (LUBAC), composed of SHARPIN (SHANK-associated RH domain-interacting protein), HOIL-1L (longer isoform of heme-oxidized iron-regulatory protein 2 ubiquitin ligase-1), and HOIP (HOIL-1L interacting protein), forms linear ubiquitin on nuclear factor-κB (NF-κB) e...

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Detalles Bibliográficos
Autores principales: Yamamotoya, Takeshi, Nakatsu, Yusuke, Matsunaga, Yasuka, Fukushima, Toshiaki, Yamazaki, Hiroki, Kaneko, Sunao, Fujishiro, Midori, Kikuchi, Takako, Kushiyama, Akifumi, Tokunaga, Fuminori, Asano, Tomoichiro, Sakoda, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343862/
https://www.ncbi.nlm.nih.gov/pubmed/28165393
http://dx.doi.org/10.3390/ijms18020326

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