Multinucleated Giant Cancer Cells Produced in Response to Ionizing Radiation Retain Viability and Replicate Their Genome

Loss of wild-type p53 function is widely accepted to be permissive for the development of multinucleated giant cells. However, whether therapy-induced multinucleation is associated with cancer cell death or survival remains controversial. Herein, we demonstrate that exposure of p53-deficient or p21(...

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Detalles Bibliográficos
Autores principales: Mirzayans, Razmik, Andrais, Bonnie, Scott, April, Wang, Ying W., Kumar, Piyush, Murray, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343895/
https://www.ncbi.nlm.nih.gov/pubmed/28208747
http://dx.doi.org/10.3390/ijms18020360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343895/
https://www.ncbi.nlm.nih.gov/pubmed/28208747
http://dx.doi.org/10.3390/ijms18020360

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