Cargando…

Vanillin Protects Dopaminergic Neurons against Inflammation-Mediated Cell Death by Inhibiting ERK1/2, P38 and the NF-κB Signaling Pathway

Neuroinflammation plays a very important role in the pathogenesis of Parkinson’s disease (PD). After activation, microglia produce pro-inflammatory mediators that damage surrounding neurons. Consequently, the inhibition of microglial activation might represent a new therapeutic approach of PD. Vanil...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Xuan, Liu, Dian-Feng, Zhang, Xiang-Yang, Liu, Dong, Xu, Shi-Yao, Chen, Guang-Xin, Huang, Bing-Xu, Ren, Wen-Zhi, Wang, Wei, Fu, Shou-Peng, Liu, Ju-Xiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343924/ https://www.ncbi.nlm.nih.gov/pubmed/28208679 http://dx.doi.org/10.3390/ijms18020389

Ejemplares similares

Peiminine Protects Dopaminergic Neurons from Inflammation-Induced Cell Death by Inhibiting the ERK1/2 and NF-κB Signalling Pathways
por: Chen, Guangxin, et al.
Publicado: (2018)

GLP-2 Attenuates LPS-Induced Inflammation in BV-2 Cells by Inhibiting ERK1/2, JNK1/2 and NF-κB Signaling Pathways
por: Li, Nan, et al.
Publicado: (2016)

Schizandrin C regulates lipid metabolism and inflammation in liver fibrosis by NF-κB and p38/ERK MAPK signaling pathways
por: Chen, Panpan, et al.
Publicado: (2023)

Peiminine Protects against Lipopolysaccharide-Induced Mastitis by Inhibiting the AKT/NF-κB, ERK1/2 and p38 Signaling Pathways
por: Gong, Qian, et al.
Publicado: (2018)

Influence of pentylenetetrazol and NF-κB decoy oligodeoxynucleotides on p38 expression in neuron-like cells
por: YANG, JIA-JUN, et al.
Publicado: (2014)

Farrerol Relieve Lipopolysaccharide (LPS)-Induced Mastitis by Inhibiting AKT/NF-κB p65, ERK1/2 and P38 Signaling Pathway
por: Li, Yanwei, et al.
Publicado: (2018)

Retinal neuronal MCP-1 induced by AGEs stimulates TNF-α expression in rat microglia via p38, ERK, and NF-κB pathways
por: Dong, Ning, et al.
Publicado: (2014)

Differential Role of ERK and p38 on NF-κB Activation in Helicobacter pylori-Infected Gastric Epithelial Cells
por: Seo, Ji Hye, et al.
Publicado: (2013)

Kinsenoside Ameliorates Oxidative Stress-Induced RPE Cell Apoptosis and Inhibits Angiogenesis via Erk/p38/NF-κB/VEGF Signaling
por: Luo, Xu, et al.
Publicado: (2018)

IL-8 promotes inflammatory mediators and stimulates activation of p38 MAPK/ERK-NF-κB pathway and reduction of JNK in HNSCC
por: Chan, Leong-Perng, et al.
Publicado: (2017)

Involvement of the ERK pathway in the protective effects of glycyrrhizic acid against the MPP(+)-induced apoptosis of dopaminergic neuronal cells
por: TENG, LESHENG, et al.
Publicado: (2014)

Amyloid β Peptide Enhances RANKL-Induced Osteoclast Activation through NF-κB, ERK, and Calcium Oscillation Signaling
por: Li, Shangfu, et al.
Publicado: (2016)

Koumine Attenuates Lipopolysaccaride-Stimulated Inflammation in RAW264.7 Macrophages, Coincidentally Associated with Inhibition of NF-κB, ERK and p38 Pathways
por: Yuan, Zhihang, et al.
Publicado: (2016)

Elevated P75(NTR )expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression
por: Alavian, Kambiz N, et al.
Publicado: (2009)

Role of GABA(B) receptors and p38MAPK/NF-κB pathway in paclitaxel-induced apoptosis of hippocampal neurons
por: Li, Zhao, et al.
Publicado: (2017)

BHBA Suppresses LPS-Induced Inflammation in BV-2 Cells by Inhibiting NF-κB Activation
por: Fu, Shou-Peng, et al.
Publicado: (2014)

ERK-mediated NF-κB activation through ASIC1 in response to acidosis
por: Chen, B, et al.
Publicado: (2016)

Death receptor 6 (DR6) is required for mouse B16 tumor angiogenesis via the NF-κB, P38 MAPK and STAT3 pathways
por: Yang, X, et al.
Publicado: (2016)

Vaccaria hypaphorine alleviates lipopolysaccharide-induced inflammation via inactivation of NFκB and ERK pathways in Raw 264.7 cells
por: Sun, Haijian, et al.
Publicado: (2017)

Koumine Promotes ROS Production to Suppress Hepatocellular Carcinoma Cell Proliferation Via NF-κB and ERK/p38 MAPK Signaling
por: Yuan, Zhihang, et al.
Publicado: (2019)

Oxymatrine Inhibits Influenza A Virus Replication and Inflammation via TLR4, p38 MAPK and NF-κB Pathways
por: Dai, Jian-Ping, et al.
Publicado: (2018)

Strategies for improving the production of bio-based vanillin
por: Liu, Ying, et al.
Publicado: (2023)

Exopolysaccharides of Bacillus amyloliquefaciens Amy-1 Mitigate Inflammation by Inhibiting ERK1/2 and NF-κB Pathways and Activating p38/Nrf2 Pathway
por: Sung, Wei-Wen, et al.
Publicado: (2022)

The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-κB signaling
por: Sole, Carme, et al.
Publicado: (2004)

Calycosin protects against chronic prostatitis in rats via inhibition of the p38MAPK/NF-κB pathway
por: Wang, Heng, et al.
Publicado: (2023)

The Inhibitory Effects of Vanillin on the Growth of Melanoma by Reducing Nuclear Factor-κB Activation
por: Pourhadi, Marjan, et al.
Publicado: (2022)

Vindoline Attenuates Osteoarthritis Progression Through Suppressing the NF-κB and ERK Pathways in Both Chondrocytes and Subchondral Osteoclasts
por: Zhu, Meisong, et al.
Publicado: (2022)

Camel Milk Mitigates Cyclosporine-Induced Renal Damage in Rats: Targeting p38/ERK/JNK MAPKs, NF-κB, and Matrix Metalloproteinases
por: Arab, Hany H., et al.
Publicado: (2021)

Vanillin oxime inhibits lung cancer cell proliferation and activates apoptosis through JNK/ERK-CHOP pathway
por: Shen, Jie, et al.
Publicado: (2021)

Natural Hirudin Increases Rat Flap Viability by Anti-Inflammation via PARs/p38/NF-κB Pathway
por: Peng, Liu, et al.
Publicado: (2015)

Quercetin Protects against MPP(+)/MPTP-Induced Dopaminergic Neuron Death in Parkinson's Disease by Inhibiting Ferroptosis
por: Lin, Zhi-Hao, et al.
Publicado: (2022)

β-Sitosterol Alleviates Inflammatory Response via Inhibiting the Activation of ERK/p38 and NF-κB Pathways in LPS-Exposed BV2 Cells
por: Sun, Yanan, et al.
Publicado: (2020)

Azilsartan Modulates HMGB1/NF-κB/p38/ERK1/2/JNK and Apoptosis Pathways during Renal Ischemia Reperfusion Injury
por: Alaaeldin, Rania, et al.
Publicado: (2023)

Activity of Ligustrum vulgare L extracts against acute pancreatitis in murine models by regulation of p38 MAPK and NF-κB signaling pathways
por: Zhang, Jing, et al.
Publicado: (2022)

GBE50 Attenuates Inflammatory Response by Inhibiting the p38 MAPK and NF-κB Pathways in LPS-Stimulated Microglial Cells
por: He, Gai-ying, et al.
Publicado: (2014)

Rubidium Chloride Targets Jnk/p38-Mediated NF-κB Activation to Attenuate Osteoclastogenesis and Facilitate Osteoblastogenesis
por: Ouyang, Zhengxiao, et al.
Publicado: (2019)

Effects of Electroacupuncture on Chronic Unpredictable Mild Stress Rats Depression-Like Behavior and Expression of p-ERK/ERK and p-P38/P38
por: Xu, Jian, et al.
Publicado: (2015)

Forsythiaside inhibited titanium particle-induced inflammation via the NF-κB signaling pathway and RANKL-induced osteoclastogenesis and titanium particle-induced periprosthetic osteolysis via JNK, p38, and ERK signaling pathways
por: Xu, Kaihang, et al.
Publicado: (2019)

Silencing of the Pink1 Gene Expression by Conditional RNAi Does Not Induce Dopaminergic Neuron Death in Mice
por: Zhou, Hongxia, et al.
Publicado: (2007)

Reciprocal Role of ERK and Nf-κb Pathways in Survival and Activation of Osteoclasts
por: Miyazaki, Tsuyoshi, et al.
Publicado: (2000)

Cannot write session to /tmp/vufind_sessions/sess_tnf3c5ch16dvefdosiff0ftsqj