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A Conjugate Based on Anti-HER2 Diaffibody and Auristatin E Targets HER2-Positive Cancer Cells
Antibody-drug conjugates (ADCs) have recently emerged as efficient and selective cancer treatment therapeutics. Currently, alternative forms of drug carriers that can replace monoclonal antibodies are under intensive investigation. Here, a cytotoxic conjugate of an anti-HER2 (Human Epidermal Growth...
Autores principales: | Serwotka-Suszczak, Anna M., Sochaj-Gregorczyk, Alicja M., Pieczykolan, Jerzy, Krowarsch, Daniel, Jelen, Filip, Otlewski, Jacek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343935/ https://www.ncbi.nlm.nih.gov/pubmed/28216573 http://dx.doi.org/10.3390/ijms18020401 |
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