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A Plant Proteinase Inhibitor from Enterolobium contortisiliquum Attenuates Pulmonary Mechanics, Inflammation and Remodeling Induced by Elastase in Mice
Proteinase inhibitors have been associated with anti-inflammatory and antioxidant activities and may represent a potential therapeutic treatment for emphysema. Our aim was to evaluate the effects of a plant Kunitz proteinase inhibitor, Enterolobium contortisiliquum trypsin inhibitor (EcTI), on sever...
Autores principales: | Theodoro-Júnior, Osmar Aparecido, Righetti, Renato Fraga, Almeida-Reis, Rafael, Martins-Oliveira, Bruno Tadeu, Oliva, Leandro Vilela, Prado, Carla Máximo, Saraiva-Romanholo, Beatriz Mangueira, Leick, Edna Aparecida, Pinheiro, Nathalia Montouro, Lobo, Yara Aparecida, Martins, Mílton de Arruda, Oliva, Maria Luiza Vilela, Tibério, Iolanda de Fátima Lopes Calvo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343937/ https://www.ncbi.nlm.nih.gov/pubmed/28216579 http://dx.doi.org/10.3390/ijms18020403 |
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