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Preventive Effects of Pentoxifylline on the Development of Colonic Premalignant Lesions in Obese and Diabetic Mice

Obesity and its related metabolic abnormalities, including enhanced oxidative stress and chronic inflammation, are closely related to colorectal tumorigenesis. Pentoxifylline (PTX), a methylxanthine derivative, has been reported to suppress the production of tumor necrosis factor (TNF)-α and possess...

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Detalles Bibliográficos
Autores principales:	Fukuta, Kazufumi, Shirakami, Yohei, Maruta, Akinori, Obara, Koki, Iritani, Soichi, Nakamura, Nobuhiko, Kochi, Takahiro, Kubota, Masaya, Sakai, Hiroyasu, Tanaka, Takuji, Shimizu, Masahito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343947/ https://www.ncbi.nlm.nih.gov/pubmed/28212276 http://dx.doi.org/10.3390/ijms18020413

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