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Next-Generation Sequencing Approach in Methylation Analysis of HNF1B and GATA4 Genes: Searching for Biomarkers in Ovarian Cancer

DNA methylation is well-known to be associated with ovarian cancer (OC) and has great potential to serve as a biomarker in monitoring response to therapy and for disease screening. The purpose of this study was to investigate methylation of HNF1B and GATA4 and correlate detected methylation with cli...

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Detalles Bibliográficos
Autores principales: Bubancova, Ivana, Kovarikova, Helena, Laco, Jan, Ruszova, Ema, Dvorak, Ondrej, Palicka, Vladimir, Chmelarova, Marcela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344006/
https://www.ncbi.nlm.nih.gov/pubmed/28241454
http://dx.doi.org/10.3390/ijms18020474