Role of HGF–MET Signaling in Primary and Acquired Resistance to Targeted Therapies in Cancer

The Hepatocyte growth factor (HGF)—mesenchymal-epithelial transition (MET) pathway is deregulated in several cancers and is associated with aggressive phenotype and worse prognosis. MET, a tyrosine kinase receptor activated by HGF, plays a physiological role in embryogenesis, promoting cell growth,...

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Detalles Bibliográficos
Autores principales: Della Corte, Carminia Maria, Fasano, Morena, Papaccio, Federica, Ciardiello, Fortunato, Morgillo, Floriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344276/
https://www.ncbi.nlm.nih.gov/pubmed/28548075
http://dx.doi.org/10.3390/biomedicines2040345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344276/
https://www.ncbi.nlm.nih.gov/pubmed/28548075
http://dx.doi.org/10.3390/biomedicines2040345

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