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Role of HGF–MET Signaling in Primary and Acquired Resistance to Targeted Therapies in Cancer

The Hepatocyte growth factor (HGF)—mesenchymal-epithelial transition (MET) pathway is deregulated in several cancers and is associated with aggressive phenotype and worse prognosis. MET, a tyrosine kinase receptor activated by HGF, plays a physiological role in embryogenesis, promoting cell growth,...

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Detalles Bibliográficos
Autores principales:	Della Corte, Carminia Maria, Fasano, Morena, Papaccio, Federica, Ciardiello, Fortunato, Morgillo, Floriana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344276/ https://www.ncbi.nlm.nih.gov/pubmed/28548075 http://dx.doi.org/10.3390/biomedicines2040345

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