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Epigenomic landscape of 5-hydroxymethylcytosine reveals its transcriptional regulation of lncRNAs in colorectal cancer

BACKGROUND: DNA methylation at the 5 position of cytosine (5mC) can be converted to 5-hydroxymethylcytosine (5hmC) by the ten–eleven translocation family. The loss of global levels of 5hmC has been regarded as a hallmark in various cancers. 5-hydroxymethylcytosine is distributed at protein-coding ge...

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Detalles Bibliográficos
Autores principales:	Hu, Hanyang, Shu, Maoguo, He, Lin, Yu, Xueyuan, Liu, Xiangyu, Lu, Yalin, Chen, Yinghong, Miao, Xiaoping, Chen, Xiaohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Genetics & Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344292/ https://www.ncbi.nlm.nih.gov/pubmed/28141796 http://dx.doi.org/10.1038/bjc.2016.457

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