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The predictive and prognostic value of tumour necrosis in muscle invasive bladder cancer patients receiving radiotherapy with or without chemotherapy in the BC2001 trial (CRUK/01/004)

BACKGROUND: Severe chronic hypoxia is associated with tumour necrosis. In patients with muscle invasive bladder cancer (MIBC), necrosis is prognostic for survival following surgery or radiotherapy and predicts benefit from hypoxia modification of radiotherapy. Adding mitomycin C (MMC) and 5-fluorour...

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Detalles Bibliográficos
Autores principales:	Choudhury, Ananya, West, Catharine M, Porta, Nuria, Hall, Emma, Denley, Helen, Hendron, Carey, Lewis, Rebecca, Hussain, Syed A, Huddart, Robert, James, Nicholas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344298/ https://www.ncbi.nlm.nih.gov/pubmed/28125821 http://dx.doi.org/10.1038/bjc.2017.2

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